Bilateral cooperation Romania-Bulgaria

Optimization of photodetection and photodynamic inactivation on microbial species

Domain: Life sciences and biotechnology

Duration: January 2008- November 2009

A. Romanian partner: National Institute of R&D for Optoelectronics INOE 2000

      • Project manager: PhD Gabriela Pavelescu / PhD. Eng. Mihaela Antonina Calin
      • Young researcher: M.Sc Elfrida M. Carstea, PhD Student

B. Bulgarian partner: Institute of Electronics, Bulgarian Academy of Science

      • Project manager: Assoc. Prof. PhD Latchezar Avramov

Project description:

Main goal of this bilateral project is to exchange knowledge, as well as training and learning of new methodological approaches for Bulgarian and Romanian teams in the field of fluorescence spectroscopy of microbial species in liquids and solid surfaces, photodetection using autofluorescence, as well as photodynamic inactivation studies for evaluation of their applicability for biomedical and ecological applications.

Objectives:

  • Optimized methodology for evaluation of concentration of organic pollutants in water samples and clinical surfaces using florescence and scattering spectral techniques
  • Optimized methodology for photodynamic inactivation of bacterial contaminants on liquids and solid surfaces
  • Optical methods in clinical use: fluorescence spectroscopy and optical coherence tomography

Main results:

  • Methodology for evaluation of organic pollutants in water samples using fluorescence spectroscopy
  • Combined methods LIFs-OCT for characterization of skin affections
  • CoBil-BG fluorescence database (password contact)

    • ISI journals:

  • Light-induced fluorescence spectroscopy and optical coherence tomography of basal cell carcinoma,  E. Borisova, E. M. Carstea, L. Cristescu, E. Pavlova, N. Hadjiolov, P. Troyanova L. Avramov, Journal of Innovative Optical Health Sciences, Vol. 2, No. 3 (2009) 1–8
  • Fluorescence evaluation of anthropogenic influence on rivers crossing Sofia, E. Borisova, G. Pavelescu, A. Daskalova, L. Cristescu, E.M. Carstea, accepted for publication in Romanian Reports in Physics, 2010
  • Photodynamic inactivation of Aeromonas hydrophila by cationic phthalocyanines with diferent hydrophobicity, V. Kussovski, V. Mantareva, I. Angelov, P. Orozova, D. Wohrle, G. Schnurpfeil, E. Borisova,  L. Avramov, FEMS Microbiol Lett, Volume 294 (2009), no. 2, pp. 133–140

    Proceedings:

  • Evaluation of the anthropogenic impact on surface water systems: case of Lower Arges Basin, Romania, E. M. Carstea, G. Pavelescu, C. Ioja, L. Cristescu, Proc. 8th World Wide Workshop for Young Environmental Scientists WWW-YES 2009: Urban waters: resource or risks?, p. 110-116
  • Fluorescence fingerprints of different surface aquatic systems, L. Cristescu, E. M. Carstea, G. Pavelescu, E. Borisova, A. Daskalova, Proc. International Symposium “The Environment and Industry“, p. 253-258

    Conferences:

  • Optical coherence tomography applied to skin cancer evaluation, E. Borisova, A. Daskalova, E.M. Carstea, L. Cristescu, D. Savastru, 10th Internaltional Balkan Workshop on Applied Physics IBWAP 2009, July 06-08, 2009, Constanta, Romania
  • Skin cancer evaluation by optical coherence tomography cancer evaluation,  E.M. Carstea, E. Borisova, A. Daskalova, L. Cristescu, Sesiunea stiintifica anuala a Facultatii de Fizica, June 5th 2009, Bucharest, Romania
  • Multispectral autofluorescence diagnosis of non-melanoma skin tumors, E. Borisova, E. Pavlova, P.Troynova, D. Dogandjiiska, L.Avramov, 13th Congress of the European Society for Photobiology in conjunction with the 2nd Conference of the European Platform for Photodynamic Medicine (EPPM), Wroclaw, Poland, 2009

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